A potent alkaloid found naturally in kratom leaves in trace amounts (typically <0.04% of total alkaloid content). It is approximately 13 times more potent than morphine and 60 times more potent than mitragynine. Many modern kratom products are enhanced with synthetic or extracted 7-OH.
The primary alkaloid in kratom leaves, comprising 60-66% of total alkaloid content (1-2% of leaf weight). It is responsible for most of kratom's effects and is the standard measurement for kratom potency.
A minor alkaloid comprising 5-9% of kratom's total alkaloid content. Acts as a smooth muscle relaxer and may modulate the effects of other alkaloids.
The third most abundant alkaloid in kratom, typically comprising 6-9% of total alkaloid content. Less potent than mitragynine but contributes to kratom's overall effects profile.
Naturally occurring organic compounds containing nitrogen, typically with pharmacological effects. Kratom contains over 40 alkaloids, with mitragynine and 7-hydroxymitragynine being the most studied.
Official laboratory document detailing test results for a specific batch of product. COAs include alkaloid content, contamination testing, batch numbers, and testing methodologies.
Techniques used to concentrate alkaloids from kratom leaf, including water extraction, alcohol extraction, CO2 extraction, and acid-base extraction. Each method has different efficiency rates and may leave different residual compounds.
Process of adjusting alkaloid content to achieve consistent potency across batches. Standardized products guarantee minimum alkaloid percentages through blending or enhancement.
The ratio indicating how much raw kratom material was used to create an extract (e.g., 10:1 means 10 grams of leaf produced 1 gram of extract). Higher ratios don't always mean higher potency due to extraction efficiency variations.
Regular kratom leaf or powder that has been fortified with additional extracted alkaloids. Enhanced products combine plain leaf with concentrated extracts to increase potency beyond natural levels.
Concentrated kratom product where alkaloids have been extracted from leaf material using water, alcohol, or other solvents. Extracts are labeled with ratios (e.g., 10:1) or percentage concentrations (e.g., 45% mitragynine).
Unprocessed or minimally processed kratom leaf powder containing natural alkaloid levels (typically 1-2% mitragynine by weight). No extraction or enhancement has been performed.
Independent laboratory analysis performed by organizations with no financial interest in the results. Third-party testing ensures unbiased verification of product claims and safety.
Unique identifier assigned to products manufactured together under the same conditions. Batch numbers enable traceability and allow specific production runs to be tested and tracked.
How closely the actual alkaloid content matches the amount claimed on product packaging. Products with ±10% variance are considered accurately labeled. Greater variances indicate quality control issues.
Analysis for toxic metals including lead, arsenic, cadmium, and mercury. Kratom can absorb heavy metals from soil, making this testing important for consumer safety.
Testing for harmful microorganisms including E. coli, Salmonella, yeast, and mold. Essential for ensuring product safety, especially for botanical products.
Testing for agricultural chemicals used during cultivation. Important for imported kratom as different countries have varying pesticide regulations.
Chemical remnants from extraction or manufacturing processes, including ethanol, methanol, acetone, and other organic solvents. Products with detectable residual solvents automatically receive an F grade due to safety concerns.
International standard for testing and calibration laboratories. Labs with this accreditation meet rigorous quality standards for technical competence and reliable results. Both Cora Science and Anresco Labs maintain this certification.
The complete composition and relative concentrations of all alkaloids present in a kratom product. A full alkaloid profile includes major alkaloids (mitragynine, 7-OH) and minor alkaloids (speciogynine, paynantheine, etc.).
The concentration of active alkaloids in a product, typically measured in milligrams per gram (mg/g) or as a percentage. Potency testing verifies whether actual alkaloid content matches label claims.
An analytical method used to detect and identify residual solvents and other volatile compounds in kratom products. GC-MS is highly sensitive and can detect contaminants at parts-per-million levels.
The primary analytical method used to measure alkaloid content in kratom products. HPLC separates compounds in a sample and measures their concentrations with high precision, typically accurate to ±5%.
This glossary is maintained by TestMyKratom to help consumers understand the technical terminology used in kratom testing and product descriptions. All definitions are based on scientific literature and industry standards.
Last updated: 1/16/2026
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